A. Katiria Gonzalez Rivera

Degree Program
: Biophysics
Faculty Advisor: Katrina Forest
Phone: (608) 265-9282
Email: gonzalezrive@wisc.edu

Current Research

I investigate various aspects of Type-4 pili. These are filaments that bacteria use with various purposes such as attachment. One of my aims is to reconstruct a functional pilus in a non- pilated E. coli using genes from N. gonorrhoeae and P. aeruginosa. I analyze pili expression using transmission electron microscopy, immunofluorescence microscopy, and western-blot. Another project includes pili assembly in a cell-free system. In addition, I use crystallography to determine the structure of a type- 4 pili ATPase. Lastly, I employ bioinformatics to study how type- 4 pili protein families have co-evolved.

Publications

Martinez-Rodriguez L, et al. (2015) Functional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same Gene. J Biol Chem. 290(32):19710-25.

Carter CW Jr, et al. (2014) The Rodin-Ohno hypothesis that two enzyme superfamilies descended from one ancestral gene: an unlikely scenario for the origins of translation that will not be dismissed. Biol Direct. 9:11.

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