Melanie A. Spero 

Melanie A. Spero

Degree Program: Microbiology
Faculty Supervisor: Tim J. Donohue
Phone: (608) 265-0689


Current Research

I am interested in the physiological role of the bioenergetic NADH dehydrogenase (complex I) in bacteria. I study complex I in the model organism Rhodobacter sphaeroides, which is known for its diverse modes of growth (aerobic and anaerobic respiration, anaerobic photosynthesis). R. sphaeroides is also very interesting because it contains two phylogenetically distinct, differentially regulated complex I operons.


Kontur WS, Ziegelhoffer EC, Spero MA, Imam S, Noguera DR, Donohue TJ. Pathways involved in reductant distribution during photobiological H(2) production by Rhodobacter sphaeroides. Appl Environ Microbiol 2011 77(20):7425-9.

Abstract (PDF)

Resume (PDF)





Biochemistry Department
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