Meet chemistry professor Lloyd Smith, a BTP trainer. He was one of the original founders of BTP and in this video he shares how the program benefits him, his laboratory, and his trainees. Leah Schaffer, a current trainee in his lab, also discusses her research. Check out the other BTP trainers in the list below. 

Active BTP Trainers



Audhya, Anjon
(608) 262-3761
Biomolecular Chemistry - understanding fundamental mechanisms by which membrane proteins, lipids, and othe rmacromolecules are transported throughout eukaryotic cells
Beebe, David J.
(608) 262-2260
Biomedical Engineering - aimed at the intelligent development and use of micro (cellular) scale technologies and phenomena to solve problems in medicine and biology; current areas of focus include the effect of microenvironment on living systems and the use of responsive materials to create autonomous systems
Blackwell, Helen E.
(608) 261-1503
Chemistry - developing an integrated chemical biology research program that uses complex molecules derived from organic synthesis to probe important problems in biology, particularly in the areas of cancer and photobiology
Block, Walter F.
(608) 265-9686
Biomedical Engineering - distributed computing, signal and image processing, MR contrast mechanisms, MR angiography and cardiac imaging - specifically designing real-time magnetic resonance acquisition and processing algorithms and systems for these procedures magnetic resonance (MR) interventional procedures
Burton, Briana M.
(608) 890-0510
Bacteriology - combining in vitro and in vivo biochemistry, microscopy, microbiology and molecular biology to study the molecular mechanism of DNA translocation across membranes
Butcher, Samuel E.
(608) 263-3890
Biochemistry - focused on understanding how RNA molecules regulate gene expression
Cai, Weibo
(608) 262-1479
Radiology - development of multimodality molecular imaging agents - positron emission tomography, optical, and magnetic resonance imaging - for early diagnosis and monitoring the efficacy of therapeutic intervention
Cavagnero, Silvia
(608) 262-5430
Chemistry - protein folding and aggregation in the cell, molecular chaperones, and biomolecular spectroscopy
Chesler, Naomi
(608) 265-8920
Biomedical Engineering - improving cardiovascular health through the integration of mechanical engineering, vascular biology, and imaging tools; advancing knowledge in these fields; and educating the next generation of leaders in cardiovascular engineering and science
Coon, Joshua J.
(608) 263-1718
Chemistry and Biomolecular Chemistry - bioanalytical chemistry - mass spectrometry
Cox, Michael M.
(608) 262-1181
Biochemistry - studying a range of bacterial enzymes involved in recombinational DNA repair, both in vivo and in vitro, to understand how DNA rearrangements occur and how they are regulated
Donohue, Timothy J.
(608) 262-4663
Bacteriology - analysis pathways and networks that microbes use to grow, generate biomass, or produce alternative fuels from sunlight or other renewable sources of energy; we are studying metabolic and regulatory pathways of the photosynthetic bacterium Rhodobacter sphaeroides. By taking advantage of the R. sphaeroides genome sequence, microarrays, proteomics, and molecular techniques we are defining how the energy in sunlight or renewable nutrients is partitioned into processes like cell growth or formation of biofuels
Engle, Jonathan W.
(608) 263-5805
Medical Physics - interested in the potential of Auger- and low energy electron-emitting radionuclides for use in targeted internal radiotherapy. We own and operate a wide variety of equipment for the production of these radionuclides, their radiochemical isolation from target materials, and their incorporation into targeting agents for delivery to sites of disease in vitro and in vivo
Fabry, Zsuzsanna
(608) 265-8716
Pathology and Laboratory Medicine - immunopathology; neuroimmunology; multiple sclerosis
Forest, Katrina T.
(608) 265-3566
Bacteriology - molecular structure and function of proteins which enable some bacteria to be pathogens, in particular, using x-ray crystallography to study the Type IV pilins
Fox, Brian G.
(608) 262-9708
Biochemistry - enzymatic mechanisms of production of unsaturated fatty acids and the degradation of xenobiotic compounds
Gasch, Audrey P.
(608) 265-0859
Genetics - how cells sense their environment, detect when there is a problem, and then mount a multi-faceted response to protect themselves against stress
Ge, Ying
(608) 263-9212
Cell and Regenerative Biology - understanding the molecular and cellular mechanisms underlying cardiovascular diseases via systems biology approaches featuring cutting-edge ultra high-resolution mass spectrometry (MS)-based comparative proteomics and metabolomics in conjunction with functional studies
Gellman, Samuel H.
(608) 262-3303
Chemistry - organic and biological chemistry, including; the design of new oligomers with well-defined folding properties ("foldamers"), and their use in antimicrobial therapy and other biomedical applications; protein origins of stability and specificity in inter- and intramolecular noncovalent interactions; new polymerization methods, including template-directed polymerization
Ginder-Vogel, Matthew
(608) 262-0768
Civil & Environmental Engineering - fundamental biogeochemical processes controlling the dynamics of nutrients and contaminants within the environment
Gourse, Richard L.
(608) 262-9813
Bacteriology - control of gene expression, primarily the mechanism of transcription initiation; focusing on the architecture of transcription complexes the relationship between structure and function in subunits of RNA polymerase, and the mechanisms by which the transcription apparatus responds to signals from inside and outside of the cell
Hittinger, Chris Todd
(608) 262-1069
Genetics - evolution of the gene networks that regulate yeast carbon metabolism, yeast biodiversity, and applications in the brewing and biofuel industries
Hoskins, Aaron A.
(608) 890-3101
Biochemistry - elucidating biochemical mechanisms in eukaryotic RNA metabolism with chemistry, biology, and single molecule analysis
Jeraj, Robert
(608) 263-8619
Medical Physics - image-guided therapy, which uses medical imaging for improving accuracy of cancer treatment; various imaging modalities, ranging from positron emission tomography (PET), magnetic resonance imaging (MRI), and computed tomography (CT) are used to assess early treatment response, which can lead to treatment modification with the goal of achieving better overall tumor control
Kalejta, Robert F.
(608) 265-5546
Oncology - human cytomegalovirus replication, latency, pathogenesis, and oncomodulation; viral manipulation of the cell cycle; viral cyclin-dependent kinases (v-Cdks); intrinsic and innage cellular antiviral defenses; ubiquitin-independent protein degradation (B)
Kamp, Timothy J.
(608) 263-1172
Medicine - ion channel proteins in the heart, the coupling of cardiac electrical activity to mechanical contraction, and the molecular mechanisms underlying heart failure. In addition, more recent efforts have focused on applications of stem cells in cardiovascular research and therapy
Keck, James L.
(608) 263-1815
Biomolecular Chemistry - examining the structural mechanisms that drive DNA replication, replication restart, recombination, and repair reactions
Keller, Nancy P.
(608) 262-9795
Medical Microbiology & Immunology, Bacteriology - identifying the molecular genetic processes controlling expression of sterigmatocystin (ST) / aflatoxin (AF) biosynthesis and host metabolites which effect fungal growth and ST/AF biosynthesis
Kreeger, Pamela K.
(608) 890-2915
Biomedical Engineering - cellular engineering, systems biology, endocrinology, cancer, and women's health
Kwan, Jason
(608) 262-3829
Pharmaceutical Sciences - to discover new natural products and their biosynthetic pathways, and to understand the role of natural products in symbiotic relationships
Landick, Robert C.
(608) 265-8475
Biochemistry - regulatory mechanisms that control gene expression through changes in RNA chain elongation in organisms ranging from bacteria and humans
Li, Lingjun
(608) 265-8491
Pharmaceutical Sciences - developing improved MS-based methods of neuropeptide and protein analysis both at large-scale and micro-scale, and providing essential information on understanding the mechanisms of neuromodulation of behaviorally relevant neural circuits and peptide evolution and peptide regulation
Lynn, David M.
(608) 262-1086
Chemical and Biological Engineering - focusing broadly on (i) the design and synthesis of soft materials and (ii) the fabrication and physical characterization of macromolecular assemblies, nanostructured materials, and interfaces
Masters, Kristyn S.
(608) 265-4052
Biomedical Engineering - biomaterials and tissue engineering
McClean, Megan
(608) 890-0416
Biomedical Engineering - systems biology, synthetic biology, cellular engineering, signal processing
McMahon, Katherine D.
(608) 265-5278
Civil and Environmental Engineering - microbial ecology of natural and engineered systems, with an emphasis on biologically mediated waste treatment processes; molecular tools used to investigate microbial community structure and function in activated sludge, subsurface environments, and freshwater bodies; metabolic engineering is used to elucidate pathways of biocatalysis and biodegradation; contribution of stress response mechanisms to population structure and performance in activated sludge; bioflocculation; phosphate metabolism; and, antibiotic resistance in environmental populations
Merrins, Matthew J.
(608)256-1901 x12848
Medicine and Biomolecular Chemistry - research centers on two features of nutrient metabolism in pancreatic islet beta cells: (1) the ability to trigger pulses of insulin release, and (2) the ability to trigger cell proliferation when the demand for insulin increases (e.g., during obesity or pregnancy). These adaptive responses to environmental stress ultimately fail in neonatal, type 1, and type 2 diabetes.
Meyerand, M. Elizabeth
(608) 263-1685
Medical Physics - Magnetic Resonance Imaging (MRI)
Murphy, Regina
(608) 262-1587
Chemical and Biological Engineering - using biophysical and biochemical approaches to better understand protein misfolding and aggregation in neurodegenerative disorders
Murphy, William L.
(608) 262-2224
Biomedical Engineering - creation of novel materials using bioinspired approaches; development of biomaterials for tissue regeneration (tissue engineering); novel approaches to drug delivery and gene therapy; delivery of developmental signals to influence stem cell activity
Pagliarini, David J.
(608) 890-3254
Biochemistry - mitochondrial biogenesis and metabolism; cell signaling; proteomics, post-transcriptional control of gene expression, regulation of mitochondrial function by post-translational modifications, and comparative mitochondrial proteomics of healthy and disease states
Patterson, Sara
(608) 262-1543
Horticulture - Developmental and genetic characterization of the abscission process and senescence in plants. Research projects on the model plant Arabidopsis, grapes, tomatoes, fonio, carnations, and roses. Additional research on the role and value of school and community gardens
Pfleger, Brian F.
(608) 890-1940
Chemical and Biological Engineering - developing microorganisms capable of producing small molecules of significant social, economic, and scientific value from renewable resources
Raman, Srivatsan
(608) 890-1036
Biochemistry - systems and synthetic biology; computational protein design combined with high-throughput phenotyping; allosteric transcription factor design; directed evolution of microbial biosynthetic pathways
Reed, Jennifer
(608) 262-0188
Chemical and Biological Engineering - using computational models to study biological systems, engineer cells, and expand our knowledge of the underlying mechanisms behind observed cellular behaviors 
Rey, Federico E.
(608) 890-2046
Bacteriology - dissecting diet by microbiota interactions that impact human health, so that therapeutic/preventive dietary recommendations can be made based on the metabolic potential of a subject's microbiome 
Romero, Philip A.
(608) 262-5943
Biochemistry - studying the design principles of proteins and how they can be applied to engineer new molecular functions
Roy, Sushmita
(608) 316-4453
Biostatistics and Medical Informatics - developing statistical computational methods to identify the networks driving cellular functions by integrating different types of genome-wide datasets that measure different aspects of the cellular state
Saha, Krishanu
(608) 316-4313
Biomedical Engineering - bringing together stem cell biology, genome engineering and biomaterials expertise to generate new tools for use with human induced pluripotent stem cells (hiPSCs) to ask unique questions about human biology and disease
Sauer, John-Demian (JD)
(608) 263-1529
Medical Microbiology & Immunology - how intracellular pathogens parasitize host cells and how the host, in turn, recognizes these pathogens and defends against them
Senes, Alessandro
(608) 890-2584
Biochemistry - biochemical, biophysical, biological, and computational techniques to understand how membrane proteins assemble
Sheets, Michael D.
(608) 262-9452
Biomolecular Chemistry - post-transcriptional control of vertebrate development; regulated mRNA translation as an important mechanism for the regulation of early cell-fate decisions in vertebrate embryos 
Sherer, Nathan
(608) 890-2551
Molecular Virology and Oncology - retroviruses have evolved to hijack specific features of their cellular hosts in ways that favor efficient viral replication. Understanding virus-host interactions can inform the development of novel antiviral strategies, and, in general, retroviruses provide great tools for probing questions of cellular function and immunity
Shusta, Eric V.
(608) 265-5103
Chemical and Biological Engineering - noninvasive delivery of small molecule pharmaceuticals and biopharmaceuticals to the brain is hindered by the presence of the blood-brain barrier; we are focused on overcoming this barrier by developing noninvasive, antibody-based delivery methods that target drugs to the brain
Skala, Melissa
(608) 316-4108
Biomedical Engineering - developing optical imaging tools that are applied to pre-clinical models for the design and development of effective therapeutic strategies, and in clinical studies to provide early detection and individualized treatment to cancer patients
Smith, Lloyd M.
(608) 263-2594
Chemistry - developing novel methods and approaches for the analysis and manipulation of biomolecules; major interest areas include biological mass spectrometry, BNA computing, surface chemistry, surface detection methods (fluorescence, surface plasomon resonance), and the analysis of genetic variations
Suen, Garret
(608) 890-3971
Bacteriology - understanding the evolution and ecology of herbivore-associated microbial communities 
Sussman, Michael R.
(608) 262-8608
Biochemistry - studying key transport and signal transducing proteins in the plasma membrane of higher plants and fungi, including the structure and function of these enzymes; also, involved in developing new genomic technologies for investigating the plasma membrane; examples include a genome wide method for creating 'knockout' plants, development of a benchtop machine for creating DNA chips 'on the fly' and the use of mass spectrometers for analyzing the plant proteome and metabilome; we focus on Arabidopsis thaliana because its genome is completely sequenced and it is easy to create mutants in any gene of interest
Thomas, Michael G.
(608) 265-7767
Bacteriology - biosynthesis of bacterial secondary metabolites, specifically those made by Streptomycetes and Cyanobacteria; through the use of genomics, genetics, biochemistry, molecular biology, and chemistry we are trying to understand the logic of how these chemically complex molecules are biosynthesized and exported by the producing bacterium, as well as how their production is regulated by the cell; once these questions have been addressed, we can begin to rationally reprogram the genetic machinery to generate new structural diversity or to increase
Venturelli, Ophelia
(608) 263-7017
Biochemistry - elucidating the network design principles that underlie dynamic responses of microbial populations and ecosystems in response to complex environmental inputs, and developing methods to construct predictable feedback control systems for targeted manipulation of microbial function, dynamics and fitness
Wang, Jue D. (Jade)
(608) 263-0307
Bacteriology - identifying a molecular interface between the DNA replication machinery and its cellular milieu, understanding the conflicts between replication and transcription, and discovering how evolutionarily divergent bacteria utilize a ubiquitous molecule for stress resistance
Zalapa, Juan E.
(608) 890-3997

Horticulture - using the latest molecular tools in conjunction with traditional plant breeding to meet current and future challenges of the cranberry industry, including increasing yield in sustainable production systems, improving berry quality and nutrition, and responding to increasingly variable and extreme climates, insects, and disease pressures

Participating BTP Trainers

Other Participating Faculty