Emily Johnson
Integrated Program in Biochemistry
Advisor
Current Research
Identifying mRNA targets of the RNA-binding protein Bicaudal-C during vertebrate development
Post-transcriptional control of gene expression is critical for embryonic development. RNA-binding proteins are key regulators of post-transcriptional events. In the Sheets lab, we focus on the RNA binding protein Bicaudal-C (Bicc1), a highly conserved translational repressor. Previous work indicates that Bicc1 contributes to development through regulation of its target mRNAs. Our lab has previously identified Bicc1 target mRNAs. In my project, I use a combination of conventional and newly developed techniques to identify additional Bicc1 target mRNAs.