University of Wisconsin–Madison
Brendan Rattin

Brendan Rattin

Cellular and Molecular Pathology

Brendan Rattin

Advisor

Krishanu Saha

Biography

Current Research

Engineering broadly-applicable CAR T Cells for Autoimmune Disease

I set out to engineer and characterize a non-viral CAR-T cell product that may be deployed to treat various auto-immune conditions by directly targeting cells involved in tissue destruction and the proinflammatory environment that supports the maintenance of autoimmune disease. Our approach will selectively eliminate cells involved in maintaining autoimmunity, while concurrently addressing cells that support the inflammatory microenvironment.